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usp22 shrna aav  (Sangon Biotech)

 
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    Structured Review

    Sangon Biotech usp22 shrna aav
    Endothelial-specific knockdown of <t>USP22</t> inhibited EndoMT and hippocampal inflammation. (A) Representative images showed the colocalization of GFP signal (green) and CD31 immunofluorescence (red) in mouse hippocampus. Scale bar: 200 μm. (B) The representative blots showed the changes in ZO-1, Claudin5, α-SMA, and iNOS expression within the hippocampus in the control group and P. gingivalis -infected mice injected <t>with</t> <t>USP22-shRNA</t> AAV. (C) Bar graph with scatter points showed the quantification of USP22 in (A) . (D) Bar graph with scatter points showed the quantification of ZO-1 in (A) . (E) Bar graph with scatter points showed the quantification of Claudin5 in (A) . (F) Bar graph with scatter points showed the quantification of α-SMA in (A) . (G) Bar graph with scatter points showed the quantification of iNOS in (A) . (H,I) Bar graphs with scatter points showed the quantification of IL-1β mRNA (H) and IL-6 mRNA (I) in the control group and P. gingivalis -infected mice injected with USP22-shRNA AAV. * p < 0.05, ** p < 0.01, and *** p < 0.001.
    Usp22 Shrna Aav, supplied by Sangon Biotech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/usp22+shrna+aav/coding+csna+sequence/pmc13021663-58-11-20
    Average 86 stars, based on 1 article reviews
    usp22 shrna aav - by Bioz Stars, 2026-10
    86/100 stars

    Images

    1) Product Images from "USP22 knockdown attenuates P. gingivalis -induced EndoMT and CNS inflammation: a link between periodontitis and neuroinflammation"

    Article Title: USP22 knockdown attenuates P. gingivalis -induced EndoMT and CNS inflammation: a link between periodontitis and neuroinflammation

    Journal: Frontiers in Neuroscience

    doi: 10.3389/fnins.2026.1790970

    Endothelial-specific knockdown of USP22 inhibited EndoMT and hippocampal inflammation. (A) Representative images showed the colocalization of GFP signal (green) and CD31 immunofluorescence (red) in mouse hippocampus. Scale bar: 200 μm. (B) The representative blots showed the changes in ZO-1, Claudin5, α-SMA, and iNOS expression within the hippocampus in the control group and P. gingivalis -infected mice injected with USP22-shRNA AAV. (C) Bar graph with scatter points showed the quantification of USP22 in (A) . (D) Bar graph with scatter points showed the quantification of ZO-1 in (A) . (E) Bar graph with scatter points showed the quantification of Claudin5 in (A) . (F) Bar graph with scatter points showed the quantification of α-SMA in (A) . (G) Bar graph with scatter points showed the quantification of iNOS in (A) . (H,I) Bar graphs with scatter points showed the quantification of IL-1β mRNA (H) and IL-6 mRNA (I) in the control group and P. gingivalis -infected mice injected with USP22-shRNA AAV. * p < 0.05, ** p < 0.01, and *** p < 0.001.
    Figure Legend Snippet: Endothelial-specific knockdown of USP22 inhibited EndoMT and hippocampal inflammation. (A) Representative images showed the colocalization of GFP signal (green) and CD31 immunofluorescence (red) in mouse hippocampus. Scale bar: 200 μm. (B) The representative blots showed the changes in ZO-1, Claudin5, α-SMA, and iNOS expression within the hippocampus in the control group and P. gingivalis -infected mice injected with USP22-shRNA AAV. (C) Bar graph with scatter points showed the quantification of USP22 in (A) . (D) Bar graph with scatter points showed the quantification of ZO-1 in (A) . (E) Bar graph with scatter points showed the quantification of Claudin5 in (A) . (F) Bar graph with scatter points showed the quantification of α-SMA in (A) . (G) Bar graph with scatter points showed the quantification of iNOS in (A) . (H,I) Bar graphs with scatter points showed the quantification of IL-1β mRNA (H) and IL-6 mRNA (I) in the control group and P. gingivalis -infected mice injected with USP22-shRNA AAV. * p < 0.05, ** p < 0.01, and *** p < 0.001.

    Techniques Used: Knockdown, Immunofluorescence, Expressing, Control, Infection, Injection, shRNA

    Related Articles

    Infection:

    Article Title: USP22 knockdown attenuates P. gingivalis -induced EndoMT and CNS inflammation: a link between periodontitis and neuroinflammation
    Article Snippet: .. Prior to establishing the oral infection model, microinjection of control or USP22-shRNA AAV (CD144 promoter, 1.5 × 10 12 vg/μL; Sangon Biotech) was performed to target the mouse hippocampus bilaterally. ..

    Microinjection:

    Article Title: USP22 knockdown attenuates P. gingivalis -induced EndoMT and CNS inflammation: a link between periodontitis and neuroinflammation
    Article Snippet: .. Prior to establishing the oral infection model, microinjection of control or USP22-shRNA AAV (CD144 promoter, 1.5 × 10 12 vg/μL; Sangon Biotech) was performed to target the mouse hippocampus bilaterally. ..

    Control:

    Article Title: USP22 knockdown attenuates P. gingivalis -induced EndoMT and CNS inflammation: a link between periodontitis and neuroinflammation
    Article Snippet: .. Prior to establishing the oral infection model, microinjection of control or USP22-shRNA AAV (CD144 promoter, 1.5 × 10 12 vg/μL; Sangon Biotech) was performed to target the mouse hippocampus bilaterally. ..

    Bioprocessing:

    Article Title: USP22 knockdown attenuates P. gingivalis -induced EndoMT and CNS inflammation: a link between periodontitis and neuroinflammation
    Article Snippet: .. Prior to establishing the oral infection model, microinjection of control or USP22-shRNA AAV (CD144 promoter, 1.5 × 10 12 vg/μL; Sangon Biotech) was performed to target the mouse hippocampus bilaterally. ..



    Similar Products

    usp22 shrna aav  (Sangon Biotech)
    86
    Sangon Biotech usp22 shrna aav
    Endothelial-specific knockdown of <t>USP22</t> inhibited EndoMT and hippocampal inflammation. (A) Representative images showed the colocalization of GFP signal (green) and CD31 immunofluorescence (red) in mouse hippocampus. Scale bar: 200 μm. (B) The representative blots showed the changes in ZO-1, Claudin5, α-SMA, and iNOS expression within the hippocampus in the control group and P. gingivalis -infected mice injected <t>with</t> <t>USP22-shRNA</t> AAV. (C) Bar graph with scatter points showed the quantification of USP22 in (A) . (D) Bar graph with scatter points showed the quantification of ZO-1 in (A) . (E) Bar graph with scatter points showed the quantification of Claudin5 in (A) . (F) Bar graph with scatter points showed the quantification of α-SMA in (A) . (G) Bar graph with scatter points showed the quantification of iNOS in (A) . (H,I) Bar graphs with scatter points showed the quantification of IL-1β mRNA (H) and IL-6 mRNA (I) in the control group and P. gingivalis -infected mice injected with USP22-shRNA AAV. * p < 0.05, ** p < 0.01, and *** p < 0.001.
    Usp22 Shrna Aav, supplied by Sangon Biotech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/usp22+shrna+aav/coding+csna+sequence/pmc13021663-58-11-20
    Average 86 stars, based on 1 article reviews
    usp22 shrna aav - by Bioz Stars, 2026-10
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    Endothelial-specific knockdown of USP22 inhibited EndoMT and hippocampal inflammation. (A) Representative images showed the colocalization of GFP signal (green) and CD31 immunofluorescence (red) in mouse hippocampus. Scale bar: 200 μm. (B) The representative blots showed the changes in ZO-1, Claudin5, α-SMA, and iNOS expression within the hippocampus in the control group and P. gingivalis -infected mice injected with USP22-shRNA AAV. (C) Bar graph with scatter points showed the quantification of USP22 in (A) . (D) Bar graph with scatter points showed the quantification of ZO-1 in (A) . (E) Bar graph with scatter points showed the quantification of Claudin5 in (A) . (F) Bar graph with scatter points showed the quantification of α-SMA in (A) . (G) Bar graph with scatter points showed the quantification of iNOS in (A) . (H,I) Bar graphs with scatter points showed the quantification of IL-1β mRNA (H) and IL-6 mRNA (I) in the control group and P. gingivalis -infected mice injected with USP22-shRNA AAV. * p < 0.05, ** p < 0.01, and *** p < 0.001.

    Journal: Frontiers in Neuroscience

    Article Title: USP22 knockdown attenuates P. gingivalis -induced EndoMT and CNS inflammation: a link between periodontitis and neuroinflammation

    doi: 10.3389/fnins.2026.1790970

    Figure Lengend Snippet: Endothelial-specific knockdown of USP22 inhibited EndoMT and hippocampal inflammation. (A) Representative images showed the colocalization of GFP signal (green) and CD31 immunofluorescence (red) in mouse hippocampus. Scale bar: 200 μm. (B) The representative blots showed the changes in ZO-1, Claudin5, α-SMA, and iNOS expression within the hippocampus in the control group and P. gingivalis -infected mice injected with USP22-shRNA AAV. (C) Bar graph with scatter points showed the quantification of USP22 in (A) . (D) Bar graph with scatter points showed the quantification of ZO-1 in (A) . (E) Bar graph with scatter points showed the quantification of Claudin5 in (A) . (F) Bar graph with scatter points showed the quantification of α-SMA in (A) . (G) Bar graph with scatter points showed the quantification of iNOS in (A) . (H,I) Bar graphs with scatter points showed the quantification of IL-1β mRNA (H) and IL-6 mRNA (I) in the control group and P. gingivalis -infected mice injected with USP22-shRNA AAV. * p < 0.05, ** p < 0.01, and *** p < 0.001.

    Article Snippet: Prior to establishing the oral infection model, microinjection of control or USP22-shRNA AAV (CD144 promoter, 1.5 × 10 12 vg/μL; Sangon Biotech) was performed to target the mouse hippocampus bilaterally.

    Techniques: Knockdown, Immunofluorescence, Expressing, Control, Infection, Injection, shRNA